A.R. Life Science Pvt. Ltd.: Leaders in Revefenacin and Racecadotril Intermediate Manufacturing

A.R. Life Science Pvt. Ltd., headquartered in Hyderabad, India, is a renowned name in the pharmaceutical industry. Specializing in producing high-quality Active Pharmaceutical Ingredients (APIs) and intermediates, the company is a trusted partner for pharmaceutical companies worldwide. Among its diverse product portfolio is 2-Benzylacrylic Acid (CAS No. 5669-19-2), a critical intermediate for the synthesis of drugs like Revefenacin and Racecadotril.

This blog delves into the benefits, mechanism of action, therapeutic applications, and properties of 2-Benzylacrylic Acid, showcasing why A.R. Life Science is a leader in pharmaceutical manufacturing.

Overview of 2-Benzylacrylic Acid (CAS No. 5669-19-2)

• Product Name: 2-Benzylacrylic Acid


• CAS No.: 5669-19-2


• Molecular Formula: C10H10O2


• Molecular Weight: 162.19 g/mol


• MDL No.: MFCD00854174


• Purity/Specification: >98%


• Storage Conditions:
  
  
  
  • Keep in a dark place
  
  
  • Sealed in a dry container
  
  
  • Store at room temperature
  
  
  
  

Chemical and Physical Properties

• Appearance: White to light yellow crystalline powder


• Solubility: Soluble in organic solvents like ethanol, methanol, and DMSO


• Melting Point: 130–135°C


• Boiling Point: 320°C (approx.)


• Stability: Stable under recommended storage conditions

Mechanism of Action

Role in Drug Synthesis

2-Benzylacrylic Acid acts as a critical intermediate in the production of Revefenacin and Racecadotril, both of which target different therapeutic areas:

1. Revefenacin: A long-acting muscarinic antagonist (LAMA) used for the treatment of chronic respiratory diseases. It works by inhibiting muscarinic receptors in the airways, leading to bronchodilation and improved breathing for patients with chronic obstructive pulmonary disease (COPD).


2. Racecadotril: A prodrug that becomes active in the digestive tract to inhibit enkephalinase, reducing excessive fluid secretion and helping manage acute diarrhea.

Therapeutic Applications

Revefenacin

• Indication: Used for treating COPD, providing relief from symptoms such as shortness of breath, wheezing, and chronic cough.


• Benefits: Long-lasting bronchodilation with once-daily dosing for improved patient compliance.

Racecadotril

• Indication: Effective in managing acute diarrhea, especially in children, by reducing excessive water and electrolyte loss.


• Benefits: Rapid onset of action with minimal systemic side effects.

Benefits of 2-Benzylacrylic Acid

1. Pharmaceutical-Grade Purity: A.R. Life Science ensures >98% purity, making it a reliable choice for drug synthesis.


2. Enhanced Drug Efficacy: High-quality intermediates like 2-Benzylacrylic Acid contribute to the superior performance of the final medication.


3. Versatile Applications: Its role in the production of both respiratory and gastrointestinal drugs underscores its importance in diverse therapeutic areas.


4. Cost-Effective Manufacturing: Facilitates efficient synthesis, reducing overall production costs for pharmaceutical companies.

Why A.R. Life Science Pvt. Ltd.?

1. Commitment to Quality

A.R. Life Science adheres to stringent quality control processes, ensuring the highest standards in intermediate production.

2. Advanced Manufacturing Facilities

The company leverages state-of-the-art infrastructure and innovative processes to deliver consistent product quality.

3. Experience and Expertise

With over 20 years in the pharmaceutical industry, A.R. Life Science has established itself as a trusted partner for global pharmaceutical companies.

4. Eco-Friendly Practices

The company prioritizes sustainability, adopting environmentally friendly manufacturing techniques.

Conclusion

2-Benzylacrylic Acid (CAS No. 5669-19-2), manufactured by A.R. Life Science Pvt. Ltd., is an essential intermediate for producing life-saving drugs like Revefenacin and Racecadotril. With its superior quality, consistency, and compliance with global standards, A.R. Life Science continues to lead the way in pharmaceutical manufacturing.

For pharmaceutical companies seeking reliable intermediate manufacturers, A.R. Life Science Pvt. Ltd. offers unmatched expertise, innovative solutions, and a legacy of excellence.